The Blumenauer-McClintock Amendment is a expansion of the defunding of the Department of Justice from interfering with any state that has passed its own marijuana laws. It expands on the current defunding for the Department of Justice from interfering with any state that has passed its own medical marijuana laws. The Blumenauer-McClintock Amendment specifically provides as follows:
“SEC. __. None of the funds made available by this Act to the Department of Justice may be used, with respect to any of the States ofBlumenauer-McClintock detailsAlabama, Alaska, Arizona, Arkansas, California, Colorado, Connecticut, Delaware, Florida, Georgia, Hawaii, Illinois, Indiana, Iowa, Kentucky, Louisiana, Maine, Maryland, Massachusetts, Michigan, Minnesota, Mississippi, Missouri, Montana, Nevada, New Hampshire, New Jersey, New Mexico, New York, North Carolina, North Dakota, Ohio, Oklahoma, Oregon, Pennsylvania, Rhode Island, South Carolina, Tennessee, Texas, Utah, Vermont, Virginia, Washington, West Virginia, Wisconsin, and Wyoming, to prevent any of them from implementing their own laws that authorize the use, distribution, possession, or cultivation of marijuana.”.
46 out of the 50 states are covered because that is how many states have passed laws that disagree with marijuana being a Schedule I Controlled Substance under the Controlled Substances Act of 1970. Only 4 states currently comply with federal law and have zero medical or adult use of marijuana.
Our Main story for the week – The Blumenauer-McClintock Amendment is moving forward in Congress – so please call them at (202) 224-3121.
Cannabis News Roundup for June 19, 2019
June 18, 2019, would have been Jack Herer’s 80th birthday had the legend not passed on about 10 years ago after a powerful speech at the 2009 Seattle Hempfest that helped push the State of Washington into legalization of marijuana. Jack Herer surely would have supported the Blumenauer-McClintock Amendment to help fully defund the federal war on marijuana. He is still remembered today for his tireless efforts, and lives on in his writings, his memory, and his strain of cannabis that bears his name.
For acute toxicity studies, a dose of 246 mg/kg was chosen as an initial dose as this is a MED analogous to those used in recent clinical trials (MED of 20 mg/kg CBD) [1,2]. Subsequently, we used doses of 738 and 2460 mg/kg CBD as 3× and 10× doses, respectively.
Mice at 738 mg/kg and 2460 mg/kg groups developed a sub-lethargic condition which presented as decreased appetite and slow response to exogenous stimuli at 4–5 h after CBD administration. This was still evident in mice receiving the 2460 mg/kg dose at the 24 h time-point. Administration of 2460 mg/kg CBD led to marginal body weight loss (9.5% from control) whereas the response in 738 mg/kg mice was mixed, with 4 mice exhibiting patterns of substantial weight loss (11%–15%) while two gained body weight (~10%) (Figure 1A). Further, 738 mg/kg caused significant increases in liver-to-body weight ratios (18%, p < 0.005), while 2460 mg/kg was characterized by an uneven distribution of these values (Figure 1B), even when using pre-gavage body weights to calculate organ to body weight ratios.
Basically, the scientists took the dosage for the high end of CBD for severe forms of epilepsy and multiplied it by over 100x. The highest dosage of CBD as the drug Epidiolex is 20 mg/kg – here the above excerpt from the studies indicates doses more than 10x to 100x higher. From 246 mg/kg up to 2460 mg/kg.
The study was funded by by the National Institute of General Medical Sciences [grant # P20 GM109005 to IK], the American Association for the Study of Liver Diseases (AASLD) Foundation [Pinnacle Research Award to MRM], and the Arkansas Biosciences Institute. The authors disclosed a possible conflict of interest and provided they were scientific consultants for the pharmaceutical company Allergan.
More study is needed to confirm the safety of CBD.
Tune in Next Week for More Cannabis Legalization News
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But first tell your Congress Rep to Supportthe BLUMENAUER-MCCLINTOCK AMENDMENT!!
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